Clin2
NCT06779123Possibly a fitRecruiting

Vagus nerve stimulation for rheumatoid arthritis

Rheumatoid Arthritis (RA)

Part of Bones, joints & muscles, Immune system & allergy, Pain, Skin clinical trials.

This trial tests a non-invasive device that stimulates a nerve in your ear to see if it can reduce rheumatoid arthritis symptoms. It is for people whose RA has not responded well to at least one biologic or targeted DMARD.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
128 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years or older
  • Have active rheumatoid arthritis with at least 4 tender and 4 swollen joints
  • Have tried at least one biologic or targeted DMARD (like a JAK inhibitor) that didn't work well enough or caused side effects
  • Must be on a stable dose of steroids or standard RA medications for at least 2 to 4 weeks before starting

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07870564Not yet recruiting
Ear stimulation for pain in rheumatoid arthritis

This study tests a device that sends gentle electrical pulses to your ear to help reduce pain and prevent it from becoming more widespread. It may be an option if you have rheumatoid arthritis and chronic pain that isn't fully controlled by your current medications.

NCT07274124Recruiting
Pain education and nerve stimulation for rheumatoid arthritis

This study tests whether combining pain education with a mild nerve stimulation device can improve pain and recovery in people with rheumatoid arthritis. It may help you manage long-term pain better.

Istanbul, Fatih
NCT07017686Recruiting
Reboot Study: Nerve stimulation for rheumatoid arthritis

This study tests a device that sends mild electrical pulses to the vagus nerve in the abdomen to treat rheumatoid arthritis. It is for people whose arthritis has not improved after trying multiple medications.

Fitzroy, Victoria
NCT07653009Recruiting
Nerve stimulation for psoriatic arthritis pain

This trial tests whether a gentle electrical stimulation of a nerve in the ear can reduce pain and inflammation in people with psoriatic arthritis. If you have moderate to high disease activity despite stable treatment, you may be able to join.

Istanbul
NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke

This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.

St Louis, Missouri
NCT04777500Not yet recruiting
Ear nerve stimulation for fibromyalgia

This study tests a device that stimulates a nerve in your ear (called taVNS) to see if it can help reduce fibromyalgia pain. You use the device at home twice a day for 4 weeks.

Charlestown, Massachusetts

Hear when a new Rheumatoid Arthritis (RA) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.