Clin2
NCT06781281Possibly a fitRecruiting

Chemo plus immunotherapy for early HR+/HER2- breast cancer

Breast Cancer Invasive

Treatments studied

Part of Cancer clinical trials.

This trial tests adding an immunotherapy drug (serplulimab) to standard chemotherapy for early-stage HR+/HER2- breast cancer. The goal is to see if the combination works better than chemo alone before surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
709 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 or older
  • You have early-stage breast cancer that is HR-positive and HER2-negative
  • Your tumor is at least cT2 or has spread to lymph nodes
  • You have not had any prior chemotherapy, hormone therapy, or immunotherapy for this cancer
  • You do not have cancer that has spread to other parts of your body

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06860529Recruiting· Phase 2
Immunotherapy plus chemo for early-stage HR+/HER2- breast cancer

This trial tests adding the immunotherapy drug serplulimab to standard chemotherapy for people with early-stage HR-positive, HER2-negative breast cancer. It aims to see if this combination can improve outcomes before surgery.

Zhengzhou, Henan
NCT06639672Not yet recruiting· Phase 2
Chemotherapy plus immunotherapy with different radiation doses for early-stage breast cancer

This trial tests a combination of chemotherapy, an immunotherapy drug, and two different schedules of radiation before surgery for a common type of breast cancer. The goal is to find which radiation approach works better and to improve outcomes.

NCT07317778Not yet recruiting· Phase 2
Adding immunotherapy and targeted therapy to chemotherapy for early breast cancer

This trial tests whether adding two newer drugs to standard chemotherapy can improve outcomes for women with early-stage breast cancer that is hormone-receptor positive and has low HER2. The goal is to see if a combination of immunotherapy and targeted therapy helps shrink tumors before surgery.

Beijing
NCT06611813Recruiting· Phase 2
Chemo plus immunotherapy for HR+/HER2- breast cancer

This trial tests whether adding an immunotherapy drug (toripalimab) to standard chemotherapy before surgery can help treat HR+/HER2- breast cancer. It is for women with early-stage breast cancer that has not spread to other parts of the body.

Hangzhou
NCT07254858Not yet recruiting· Phase 2
Chemo-immunotherapy plus radiation before surgery for breast cancer

This trial tests a combination of chemotherapy, immunotherapy, and targeted radiation given before surgery for a certain type of breast cancer. The goal is to see if this approach can shrink tumors and improve outcomes.

Wenzhou, Zhejiang
NCT06874933Recruiting· Phase 2
Chemo plus anlotinib and benmelstobart for HR+/HER2- breast cancer

This trial tests adding anlotinib (a targeted therapy) and benmelstobart (an immunotherapy) to standard chemotherapy before surgery for a specific type of breast cancer. It may help shrink tumors and improve outcomes for patients whose tumors have certain markers.

Hangzhou, Zhejiang

Hear when a new Breast Cancer Invasive trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.