Clin2
NCT07254858Possibly a fitNot yet recruiting

Chemo-immunotherapy plus radiation before surgery for breast cancer

HR+/HER2- Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests a combination of chemotherapy, immunotherapy, and targeted radiation given before surgery for a certain type of breast cancer. The goal is to see if this approach can shrink tumors and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
302 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been newly diagnosed with breast cancer and have not yet received treatment.
  • Your tumor is hormone receptor-positive (HR+) and HER2-negative.
  • Your tumor has a high growth rate (Ki67 ≥ 20%).
  • You have a PD-L1 CPS score that can be evaluated (tissue sample available).
  • You have good lung, liver, and kidney function, and your overall health status is good (ECOG 0-1).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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