Clin2
NCT06784193Possibly a fitRecruiting

Study of OP-3136 for advanced solid tumors

Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC)Metastatic Breast CancerFulvestrantPalazestrant

Treatments studied

Part of Cancer, Lungs & breathing, Skin clinical trials.

This trial tests a new drug, OP-3136, alone or with other drugs, for people with advanced breast cancer, prostate cancer, or lung cancer that has stopped responding to other treatments. It aims to see if OP-3136 is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have advanced or metastatic breast cancer that is ER+/HER2-, advanced prostate cancer (mCRPC), or non-small cell lung cancer (NSCLC).
  • Your cancer has spread or cannot be removed with surgery.
  • You have tried at least one prior treatment (like hormone therapy or a CDK4/6 inhibitor) and it stopped working.
  • You have not had a previous treatment with a KAT6A/B inhibitor drug.
  • Your cancer does not have active or untreated brain metastases that need treatment.
  • You do not have serious heart problems or a stroke in the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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