Brain Reorganization After Stroke (SPECTRE Trial)
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at how the brain reorganizes itself after a stroke. It focuses on people with weakness in one arm and aims to understand recovery patterns, which could help future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 74 years old.
- You had a single stroke caused by a blocked blood vessel (ischemic stroke) in the upper part of the brain, confirmed by scan.
- You have weakness in your arm or hand on the third day after your stroke.
- You do not have major trouble understanding or following instructions.
- You are covered by French social security.
- You can have an MRI scan (no metal implants or claustrophobia).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests an upper-limb (arm/hand) rehabilitation program guided by brain activity signals, started soon after a stroke. It may help people with early incomplete arm recovery improve hand and arm function.
This study uses a light-based brain scanner (fNIRS) to understand how stroke affects arm movement. It may help find new ways to improve rehab.
This study uses ultra-powerful MRI to see how the brain reorganizes after a stroke. It may help explain why some people recover arm movement and guide future therapies.
This study looks at how brain signals and MRI scans change after a first stroke that affects the arm. It tests whether these signals can help predict how well rehabilitation will work.
This study uses a special test to see how blood flows in different parts of the brain after a stroke. It helps doctors better understand stroke recovery.
This study tests a brain-training technique called neurofeedback to see if it can improve thinking skills after a stroke. If you have ongoing memory or attention problems despite recovery, this trial may help you train your brain using real-time feedback from your own brain activity.
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