Smallest effective steroid dose for spine surgery pain
Treatments studied
Part of Brain & nervous system clinical trials.
This study tests whether a very small amount of a steroid (betamethasone) placed around the surgical cut can help control pain after spine surgery. It aims to find the lowest dose that still works well, so patients may need fewer painkillers and recover more comfortably.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are scheduled for spine surgery (neck, upper back, or lower back) that involves no more than three bones.
- You are generally healthy (classified as ASA I or II by your anesthesiologist).
- You have never had spine surgery before.
- You do not have diabetes, take steroids, or abuse drugs or alcohol.
- You are not pregnant or breastfeeding, and you have no known allergies to the medicines used (ropivacaine, betamethasone, or opioids).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting a numbing medication (ropivacaine) mixed with a steroid (Diprospan) into the surgical area before chest surgery can reduce pain after the procedure. If it works, patients may need fewer pain pills and feel more comfortable during recovery.
This study tests a combination of two medications (dexmedetomidine and esketamine) to help manage moderate-to-severe pain after spine surgery. You would receive these drugs through an IV pump that you control to give yourself pain relief as needed.
This study tests whether combining two medications—dexmedetomidine and esketamine—given during and after spine surgery can reduce chronic pain that sometimes develops months or years after surgery. If it works, it could help prevent long-term pain problems for people having back or neck surgery.
This trial tests whether injecting a local anesthetic (numbing medicine) and a steroid around the surgical area before surgery reduces pain after laparoscopic procedures like gallbladder, appendix, or hernia repair. The goal is to help patients recover more comfortably with potentially less pain medication needed.
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
Hear when a new Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.