Study of IMC-001 to stabilize heart artery plaque
Part of Heart & circulation clinical trials.
This trial tests an investigational drug, IMC-001, to see if it can make artery plaques in the heart more stable and less likely to cause a heart attack. You may be eligible if you've recently had a heart attack or unstable angina and have a specific type of soft plaque in your arteries.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with acute coronary syndrome (ACS) like a heart attack or unstable angina.
- You have at least one soft plaque (not heavily calcified) in your heart artery, seen on a CT scan.
- Your C-reactive protein level is 1.0 mg/L or higher, indicating some inflammation.
- You must be willing to receive standard heart treatments during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
This trial tests whether a powerful cholesterol-lowering drug (PCSK9 inhibitor) helps stabilize plaque in heart arteries after a recent heart attack or unstable angina treated with a stent. It may lower the risk of future heart problems.
This trial tests whether implanting stents in non-obstructive, high-risk plaques (thin-capped fatty plaques) can prevent future heart attacks. It is for people who have already had treatment for a recent heart attack or unstable angina and have additional plaques that are not severely blocking blood flow but are vulnerable.
This study uses special camera catheters to look at artery plaques that are not the main cause of your current heart attack or chest pain. The goal is to find high-risk plaques early so doctors can decide the best treatment.
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Hear when a new Atherosclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.