Clinical trials
Atherosclerosis clinical trials
Below are recruiting atherosclerosis clinical trials, each written for real people, not researchers. We’re tracking 166 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07312383Recruiting
Skin blood flow study in leg artery disease
This trial uses a special device to measure tiny blood vessels in the skin of patients with severe leg artery disease. It aims to understand how blood flow changes before and after a common treatment to open blocked leg arteries (angioplasty).
OsloAges 18 years+ - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Huntsville, AlabamaAges 18–80 - NCT03504956Recruiting
MRI study to map early heart artery plaque changes
This study uses an MRI scan to better “see and measure” early changes in the heart’s artery lining. It may help researchers understand coronary artery disease earlier, even before it causes symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT07362966RecruitingPhase 4
Colchicine for heart health after a heart attack
This study tests whether a low-dose medicine called colchicine can reduce inflammation and slow down artery blockages in people who have a specific gene change (TET2) and have recently had a heart attack. The goal is to see if it helps prevent future heart problems.
Shenyang, LiaoningAges 40–85 - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT07448038RecruitingPhase 2
Study of selnoflast for heart artery inflammation
This trial tests a drug called selnoflast to see if it can reduce inflammation in the arteries of people with atherosclerosis (hardening of the arteries) who are at risk for heart attacks or other serious heart problems.
Beverly Hills, CaliforniaAges 18–80 - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT04410003RecruitingPhase 1
Stool-sample capsules to study gut microbiome in unexplained atherosclerosis
This early-phase study tests whether taking stool-based capsules can change gut bacteria in people with severe atherosclerosis that can’t be explained by usual risk factors. Researchers also measure related metabolic (body chemistry) and microbiome (gut bacteria) changes to see how this approach might help.
London, OntarioAges 18 years+ - NCT04537403RecruitingPhase 1
PET scan study of artery inflammation marker in plaque
This Phase 1 study tests whether a special PET scan can detect a specific inflammation signal (CCR2) in atherosclerosis—fatty plaque buildup in blood vessels. It may help future doctors better see which plaques are more inflamed and potentially more dangerous.
St Louis, MissouriAges 18–89 - NCT04847752Recruiting
Predicting outcomes after stroke from artery plaque
This study looks at factors that can help predict recovery and risk after an ischemic stroke caused by plaque buildup in a major artery. It may help doctors better forecast prognosis and tailor follow-up care for people like you.
WuhanAges Up to 80 years - NCT05180942Recruiting
Statins and heart plaque changes in people with melanoma on immunotherapy
This trial studies whether taking a cholesterol medicine called a statin can slow the buildup or worsening of coronary artery plaque in people with melanoma who are receiving checkpoint inhibitor (immunotherapy) treatment. It mainly looks at heart scans over time to see if statins change the progression of coronary atherosclerosis.
Kingswood, New South WalesAges 40 years+ - NCT05235464Recruiting
Testing a high-protein diet for heart plaque risk
This study checks whether eating more protein affects atherosclerosis, which is plaque buildup in artery walls. It may help researchers understand if a high-protein approach changes health markers linked to heart disease.
Columbia, MissouriAges 45–75 - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05365425RecruitingPhase 4
Choline fenofibrate to reduce plaque in type 2 diabetes
This trial studies whether choline fenofibrate can improve blood vessel plaque (carotid artery plaque) in people with type 2 diabetes and mixed cholesterol problems. It aims to see if the medicine can make carotid plaque thinner or otherwise healthier while keeping safety in mind.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT05838547Recruiting
PET-MR scan study for narrowing in the carotid artery
This study tests how well a special PET-MR scan can help evaluate carotid artery plaque in people who have significant narrowing but no symptoms. It may help researchers better understand disease activity to guide treatment decisions like medication alone or medication plus surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT06230406Recruiting
Gene study in atherosclerosis patients having surgery
This study looks at genes in people who have atherosclerosis (hardening of the arteries). It will check tissue samples taken during surgery to learn more about how the disease works.
San Donato Milanese, MilanAges Any age - NCT06253962Recruiting
Can carotid artery scans predict heart disease?
This study looks at whether ultrasound scans of the carotid artery (the main artery in your neck) can help predict blockages in the heart arteries. If you are getting both a carotid ultrasound and a heart angiogram, you may be able to join.
ShanghaiAges 14–90
Hear when a new Atherosclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Atherosclerosis trials by city
Studies with a site in or near these metro areas.
Atherosclerosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for atherosclerosis?
- Yes. Clin2 currently lists 166 recruiting atherosclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.