Clinical trials
Atherosclerosis clinical trials
Below are recruiting atherosclerosis clinical trials, each written for real people, not researchers. We’re tracking 160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07298655Recruiting
3D ultrasound to see new blood vessels in carotid plaque
This trial uses a special 3D ultrasound with contrast dye to look at fatty buildup (plaque) in the neck arteries. It aims to find new, fragile blood vessels in the plaque that might increase stroke risk.
HarrowAges 18 years+ - NCT07362966RecruitingPhase 4
Colchicine for heart health after a heart attack
This study tests whether a low-dose medicine called colchicine can reduce inflammation and slow down artery blockages in people who have a specific gene change (TET2) and have recently had a heart attack. The goal is to see if it helps prevent future heart problems.
Shenyang, LiaoningAges 40–85 - NCT07312383Recruiting
Skin blood flow study in leg artery disease
This trial uses a special device to measure tiny blood vessels in the skin of patients with severe leg artery disease. It aims to understand how blood flow changes before and after a common treatment to open blocked leg arteries (angioplasty).
OsloAges 18 years+ - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT07282041RecruitingPhase 2/Phase 3
A study on dulaglutide for brain artery narrowing after stroke
This trial tests if a once-weekly injection called dulaglutide (Trulicity) helps people with severe narrowing of a major brain artery after a minor stroke or TIA. The goal is to improve blood flow and reduce the risk of another stroke.
SingaporeAges 21–80 - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05365425RecruitingPhase 4
Choline fenofibrate to reduce plaque in type 2 diabetes
This trial studies whether choline fenofibrate can improve blood vessel plaque (carotid artery plaque) in people with type 2 diabetes and mixed cholesterol problems. It aims to see if the medicine can make carotid plaque thinner or otherwise healthier while keeping safety in mind.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT05235464Recruiting
Testing a high-protein diet for heart plaque risk
This study checks whether eating more protein affects atherosclerosis, which is plaque buildup in artery walls. It may help researchers understand if a high-protein approach changes health markers linked to heart disease.
Columbia, MissouriAges 45–75 - NCT07002697Recruiting
Study of blood vessel shape and plaque buildup
This study looks at how the shape of your blood vessels affects the buildup of plaque (atherosclerosis) and blood flow. It may help doctors better understand heart disease risk.
DhakaAges 40–70 - NCT07614230RecruitingPhase 4
SGLT2 drugs and heart artery health in diabetes
This study tests whether a diabetes medication called SGLT2 inhibitors can slow the buildup of plaque in heart arteries. Researchers will use special CT scans to track changes in your coronary arteries over time.
Beijing, Beijing MunicipalityAges 18–78 - NCT06902740RecruitingPhase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing
This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT06551805Recruiting
Ferumoxytol for better MRI images in atherosclerosis patients
This study tests whether a special iron-based contrast agent called ferumoxytol can improve MRI images of arteries affected by atherosclerosis. It may help doctors see blockages or inflammation more clearly.
Nanjing, JiangsuAges 18 years+ - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06393894Recruiting
Latvian Early Atherosclerosis Registry Study
This study is gathering information from people with early heart artery blockages (occurring before age 55 for men or 65 for women) who need or have had treatment like stents or bypass. It helps doctors understand long-term outcomes.
RigaAges 18–65 - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06253962Recruiting
Can carotid artery scans predict heart disease?
This study looks at whether ultrasound scans of the carotid artery (the main artery in your neck) can help predict blockages in the heart arteries. If you are getting both a carotid ultrasound and a heart angiogram, you may be able to join.
ShanghaiAges 14–90 - NCT06230406Recruiting
Gene study in atherosclerosis patients having surgery
This study looks at genes in people who have atherosclerosis (hardening of the arteries). It will check tissue samples taken during surgery to learn more about how the disease works.
San Donato Milanese, MilanAges Any age - NCT05838547Recruiting
PET-MR scan study for narrowing in the carotid artery
This study tests how well a special PET-MR scan can help evaluate carotid artery plaque in people who have significant narrowing but no symptoms. It may help researchers better understand disease activity to guide treatment decisions like medication alone or medication plus surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75
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Atherosclerosis trials by city
Studies with a site in or near these metro areas.
Atherosclerosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for atherosclerosis?
- Yes. Clin2 currently lists 160 recruiting atherosclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.