Divarasib plus pembrolizumab for KRAS G12C lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial compares a new targeted drug (divarasib) combined with an immunotherapy (pembrolizumab) versus standard chemotherapy plus immunotherapy for people with advanced lung cancer that has a specific KRAS G12C mutation. It aims to see if the new combination works better and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your lung cancer is advanced or metastatic and cannot be removed by surgery or treated with radiation alone.
- You have a specific mutation called KRAS G12C in your tumor.
- You have not had any prior chemotherapy or other systemic treatment for advanced lung cancer.
- You are in generally good health (able to care for yourself and up and about more than 50% of the day).
- You have at least one tumor that can be measured on scans.
- You have not had any other cancer in the last 5 years, except for certain low-risk types.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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