Study of pembrolizumab plus calderasib for KRAS G12C lung cancer after surgery
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination of two drugs (pembrolizumab and calderasib) after surgery for people with a specific type of lung cancer gene mutation called KRAS G12C. It aims to see if this therapy can help prevent the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with non-small cell lung cancer that is mainly not made of flat cells (nonsquamous).
- Your cancer is stage IIA to IIIB (N2) and has been completely removed by surgery.
- Your tumor has a specific gene change called KRAS G12C.
- No more than 12 weeks have passed since your last cancer treatment (chemotherapy or surgery).
- You are in good general health (able to take care of yourself).
- If you have HIV, hepatitis B, or hepatitis C, it must be well controlled with treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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