Ivonescimab and Trodelvy for breast cancer with brain metastases
Part of Brain & nervous system, Cancer, Skin clinical trials.
This trial tests two drugs (Ivonescimab and a Trop2 ADC) for people with triple-negative breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and help patients live longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 to 70 years old
- Triple-negative breast cancer that has spread or come back and did not respond to taxane chemotherapy
- At least one brain tumor confirmed by MRI, with a size of 1 cm or more, that has not been treated with radiation
- You can provide tissue samples from your cancer for lab tests
- Your overall health allows you to be up and around (ECOG score 0-2) and you are expected to live at least 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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