Plasma exchange for severe drug-induced liver injury with chronic liver disease
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether plasmapheresis (a blood-cleaning procedure) can help people with severe drug-induced liver injury who also have a chronic liver condition. If you qualify, you would receive this treatment to try to reduce liver damage and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have a known or unknown chronic liver disease (like cirrhosis or fatty liver).
- Your liver injury must be caused by a medication or supplement, confirmed by a doctor's assessment.
- The liver injury must be severe, with very high bilirubin (over 12 mg/dL) or a high INR (over 2), or bilirubin over 5 mg/dL with symptoms.
- You cannot have active infections, active bleeding, severe kidney problems, liver cancer, or be pregnant or breastfeeding.
- You must not be waiting for a liver transplant or have a condition like alcoholic hepatitis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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