Colchicine to prevent irregular heartbeat after heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be scheduled for elective coronary artery bypass grafting (CABG) using a heart-lung machine.
- You must be willing to sign a consent form to join the study.
- Your heart's pumping strength must be above 35% (not severely weak).
- You must not have any significant heart valve problems needing surgery.
- You must not have liver or kidney problems as defined by the trial.
- You must not have had atrial fibrillation or a pacemaker before surgery.
- You must not have an allergy to colchicine or a history of alcoholism.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
This trial tests whether colchicine can help people with paroxysmal or persistent atrial fibrillation (AF), a type of irregular heartbeat, after a successful cardioversion. It may help reduce future AF problems, depending on the results.
This trial tests whether colchicine given after cardioversion (a procedure that restores normal rhythm) helps keep the heart in normal rhythm afterward. It may help some people have fewer early returns of atrial fibrillation.
This trial tests whether a low dose of colchicine, an anti-inflammatory medication, can help prevent bypass grafts from closing after heart surgery. You would take this medication for a set period after your coronary artery bypass graft (CABG) surgery.
This trial tests whether colchicine (a medicine used for gout) can help prevent heart problems after a stent procedure (PCI). It's for people who are in the hospital getting a stent and follow standard heart care.
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