Clin2
NCT06802835Possibly a fitRecruiting

EGFR antibody plus immunotherapy and chemo for advanced nasopharyngeal cancer

Nasopharyngeal Cancinoma (NPC)Recurrent Nasopharynx CarcinomaMetastatic Nasopharyngeal Carcinoma

Treatments studied

Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.

This trial tests a combination of an EGFR antibody, a PD-1 inhibitor, and chemotherapy for people with nasopharyngeal cancer that has returned or spread after initial treatment. The goal is to see if this new mix can help shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
148 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have nasopharyngeal cancer that has come back or spread to other parts of the body.
  • You have not had any previous treatment for this recurrence or spread.
  • You are otherwise healthy enough to undergo chemotherapy, immunotherapy, and targeted therapy (good blood counts, liver and kidney function).
  • You have at least one tumor that can be measured on scans.
  • You are not pregnant and agree to use effective contraception during and for 3 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07154069Recruiting· Phase 3
Immunotherapy for advanced nasopharyngeal cancer after chemo

This trial tests if adding an immunotherapy drug (PD-1 inhibitor) after standard induction chemotherapy helps keep advanced nasopharyngeal cancer from coming back. It is for people who have completed 3 cycles of GP chemotherapy combined with a PD-1 inhibitor and have not had their cancer progress.

Guangzhou, Guangdong
NCT07129772Not yet recruiting· Phase 2
Chemotherapy and immunotherapy for locally recurrent nasopharyngeal cancer

This trial tests a combination of chemotherapy and immunotherapy (pembrolizumab) given before and after surgery for nasopharyngeal cancer that has come back locally. The goal is to see if this approach can control the cancer and improve outcomes for patients who can't have standard re-treatment.

Hong Kong
NCT07325539Recruiting· Phase 2
Radiation and immunotherapy with chemo for nose and throat cancer

This trial tests combining low-dose radiation with an immunotherapy drug (toripalimab) and chemotherapy for people whose nose and throat cancer has come back or spread. The goal is to see if this combination works better than standard treatments.

Guangzhou, Guangdong
NCT07110558Not yet recruiting· Phase 2
Radiation and immune therapy for advanced nasopharyngeal cancer

This trial tests a new treatment for nasopharyngeal cancer that adds an immune-boosting drug (toripalimab) before and after radiation therapy, while skipping radiation to the neck lymph nodes. It aims to see if this approach is effective and reduces side effects.

Guangzhou, Guangdong
NCT07756190Not yet recruiting· Phase 2
Low-dose radiation plus immunotherapy for advanced nasopharyngeal cancer

This study tests a new way to treat nasopharyngeal cancer that has spread, using a special type of radiation plus an immunotherapy drug. It is for people who cannot or choose not to have chemotherapy, and it aims to control the cancer while keeping side effects manageable.

Guangzhou, Guangdong
NCT07373990Not yet recruiting· Phase 3
Immunotherapy plus chemoradiotherapy for advanced nasopharyngeal cancer

This trial tests a new combination of an immunotherapy drug (tislelizumab) plus standard chemoradiotherapy for people with advanced nasopharyngeal carcinoma. It aims to find out if this combination is more effective than standard care alone.

Hear when a new Nasopharyngeal Cancinoma (NPC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.