Comparing two radiation doses for leukemia transplant
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether a lower or higher dose of total body irradiation works better for people with acute leukemia getting a stem cell transplant for the first time. It aims to find the safest and most effective radiation level to prepare your body for the transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have acute myeloid leukemia, acute lymphoblastic leukemia/lymphoma, or mixed/ambiguous lineage leukemia with less than 5% blast cells in your bone marrow.
- You have not had a stem cell transplant before.
- You have a matched or partially matched related or unrelated donor available.
- You are getting post-transplant cyclophosphamide to prevent graft-versus-host disease.
- Your heart, liver, and lungs are working well enough, as measured by specific tests.
- You are not pregnant or breastfeeding, and your body mass index is below 45.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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