Hyperbaric oxygen before surgery for breast cancer
Part of Cancer, Skin clinical trials.
This trial tests adding hyperbaric oxygen (breathing pure oxygen in a pressurized chamber) before standard chemotherapy for breast cancer. The goal is to see if it helps shrink the tumor more effectively before surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 60 with a first diagnosis of invasive breast cancer (not inflammatory, not eczema-like, and not a hidden breast cancer).
- Your tumor is either locally advanced (stage III except T3N1M0) or earlier stage but too large or involves lymph nodes so that breast-conserving surgery isn't an option, and you are eligible for chemo before surgery.
- You have never had hyperbaric oxygen therapy before and have no conditions that make it unsafe (like a collapsed lung, severe lung disease, middle ear problems, or retinal detachment).
- You are not pregnant or breastfeeding, and agree to use birth control during treatment and for 7 months after.
- Your heart, liver, kidney, and blood cell counts are within safe limits (as checked by your doctor) and you have an ECOG performance status of 0 or 1 (meaning you're fully active).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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