Preventing bleeding from enlarged veins in the esophagus
Part of Cancer, Digestive system clinical trials.
This study tests whether tying off high-risk veins in the esophagus before starting a common liver cancer treatment can prevent bleeding. It is for people with liver cancer that has spread but who have never had cancer treatment before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 19 and 79 years old.
- Your liver disease is mild (Child-Pugh Class A).
- Your cancer has spread beyond the liver but you haven't had any cancer treatment yet.
- You are able to care for yourself (ECOG 0 or 1) and have acceptable blood counts and liver function.
- You have had a recent upper endoscopy (within the last 6 months) to check for varices.
- You have not had any prior treatment for varices or bleeding from varices.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to prevent bleeding from enlarged veins in the esophagus (varices) in people with liver cancer and cirrhosis. One method uses a medication called carvedilol alone, while the other combines carvedilol with a procedure called band ligation, which ties off the veins to prevent bleeding.
This study compares two ways to stop variceal bleeding (bleeding from swollen veins in the esophagus or stomach) from coming back in people with liver cancer. It tests whether an ultrasound-guided technique during endoscopy can reduce repeat bleeding compared with standard endoscopy methods.
This trial compares two treatments (banding or a medication called carvedilol) to prevent the first episode of bleeding from enlarged veins in the esophagus in people with liver cancer. The goal is to find which approach is safer and more effective.
This study compares two ways to prevent future bleeding from enlarged veins in the esophagus or stomach in people with liver cirrhosis. One method uses a small tube (called TIPS) to reduce pressure in the liver, and the other combines a banding procedure with medication. The goal is to see which approach works better.
This trial tests if preventing esophageal varices (swollen veins in the food pipe) can reduce bleeding risk in people with advanced liver cancer who are receiving a combination of two drugs (atezolizumab and bevacizumab). It may help those with good liver function and no high-risk varices at the start.
This trial studies better ways to use endoscopy and other treatments to stop bleeding in the stomach or esophagus caused by high blood pressure in the liver (portal hypertension). It may help if you have been diagnosed with portal hypertension and have varices (enlarged veins) in your esophagus or stomach.
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