A drug for heart failure with obesity
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 80 years old
- Have been diagnosed with chronic heart failure for at least 1 month
- Have heart failure with preserved ejection fraction (your heart still pumps blood well but doesn't relax fully)
- Have a body mass index (BMI) of 28 or higher (considered obese)
- Be able to walk between 100 and 425 meters in 6 minutes
- Have a stable medication routine for at least 4 weeks before the trial starts
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medication called HRS-7535 for people who have high blood pressure and are also overweight or obese. The drug may help lower blood pressure and support weight loss, and this trial will compare it to a placebo to see if it works well and is safe.
This is an early-stage safety test of a new experimental drug called HRS-5765 in people without serious health conditions. Researchers want to make sure the drug is safe and understand how your body processes it.
This trial tests a new drug called HRS-1893 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug can improve symptoms and quality of life.
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
This trial compares two versions of the study drug HRS9531 in people with overweight or obesity to see which one works better in the body. It may help find a more effective treatment for weight management.
This is an early-stage safety study of an experimental drug called HRS-7156 in people with no serious health conditions. Researchers will monitor how your body tolerates the drug and how it moves through your system.
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