Testing HRS-1893 for heart failure with preserved ejection fraction
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a new drug called HRS-1893 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug can improve symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 40 years old.
- You have been diagnosed with heart failure with preserved ejection fraction (your heart pumps normally but doesn't fill properly).
- Your heart failure symptoms are mild to moderate (NYHA class II or III).
- You do not have atrial fibrillation or a history of dangerous heart rhythms.
- You have not had a heart attack or major heart blockage in the last 6 months without treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how the heart muscle works in people with a type of heart failure where the heart pumps normally but doesn't fill properly. It aims to understand the cause better, which could lead to new treatments.
This study is testing better ways to understand and manage heart failure where the heart pumps normally but still doesn't work as well as it should. It looks at people with symptoms like shortness of breath and fatigue, using blood tests and heart imaging to check eligibility.
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This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
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