NanO2 oxygen therapy for large vessel stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a special oxygen formulation (NanO2) given soon after a stroke caused by a large artery blockage. It aims to see if extra oxygen can help protect the brain while doctors work to remove the clot.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and not pregnant or breastfeeding.
- Your stroke was caused by a blockage in a large brain artery (like the main branch or a major fork).
- You can get to the hospital within 9 hours of when your symptoms started (or when you fell asleep, if you woke up with symptoms).
- You do not have serious kidney, liver, heart, or lung problems that require ongoing care.
- You have not had an allergic reaction to similar oxygen treatments before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving extra oxygen early (in the ambulance) can help protect the brain after a stroke. It is for people having a first-time stroke who can start treatment within 6 hours of symptoms.
This study tests whether giving extra oxygen (normobaric hyperoxia) along with standard clot-removal procedures helps people who have a stroke and are treated later than usual (6-24 hours after symptoms start). The goal is to improve recovery.
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
This trial tests whether giving high-concentration oxygen (normobaric oxygen) during transfer to a hospital that can remove a blood clot can help people with acute ischemic stroke. It is for patients who are being transferred specifically for endovascular therapy (EVT) to remove a large clot in the brain.
This program provides access to an investigational medicine called NanO2 for people with serious or life-threatening conditions who have no other treatment options. It aims to offer potential benefit when standard treatments have failed or are not available.
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help recovery after emergency clot-removal surgery for large blood vessel strokes. The goal is to see if extra oxygen can reduce brain damage and improve outcomes.
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