Comparing melphalan doses before stem cell transplant for AML/MDS
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial compares two different doses of a chemotherapy drug (melphalan) as part of the conditioning treatment before a stem cell transplant. The goal is to find which dose is safer and more effective for people with AML or MDS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have acute myeloid leukemia (AML) in first remission, OR myelodysplastic syndrome (MDS) with 5-20% blast cells in your bone marrow.
- You have a suitable stem cell donor (a matched sibling, a closely matched unrelated donor, or a half-matched family donor).
- You do not have an active infection that requires treatment right now.
- Your liver, kidneys, and heart are working normally or any problems are well controlled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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