Study on carbidopa/levodopa ratio for low blood pressure in MSA-P and Parkinson's
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether adjusting the ratio of carbidopa and levodopa (medications used for Parkinson's) can help reduce dizziness or fainting from low blood pressure when standing up, in people with Multiple System Atrophy (Parkinsonian type) or Parkinson's disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 79 years old.
- You have Multiple System Atrophy (parkinsonian type) or Parkinson's disease with symptoms of low blood pressure when standing (like dizziness or feeling faint).
- You are currently taking levodopa combined with carbidopa or benserazide.
- You are able to stop taking your regular levodopa medication overnight (at least 12 hours) and your extended-release dose at least 24 hours before the test.
- You do not have severe heart failure, dementia, or significant memory problems that make it hard to understand the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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