Blood pressure study in Parkinson's disease

This study tests whether adjusting the ratio of carbidopa and levodopa (medications used for Parkinson's) can help reduce dizziness or fainting from low blood pressure when standing up, in people with Multiple System Atrophy (Parkinsonian type) or Parkinson's disease.

This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.

This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.

This study is testing a smart computer system that helps doctors diagnose orthostatic hypotension (a sudden drop in blood pressure when standing) more accurately. If you have Parkinson's, MSA, or diabetes and feel dizzy when standing, this might help you get a clearer diagnosis.

This Phase 2 study tests whether the medicines droxidopa and pyridostigmine can improve symptoms of orthostatic hypotension, which is low blood pressure when you stand up. It is designed for people whose low blood pressure is caused by problems with the nerves that control blood pressure.

This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.