Pacing vs medication for heart rate control in AF with heart failure
Part of Heart & circulation clinical trials.
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had permanent atrial fibrillation for more than 6 months.
- Your heart's pumping strength (ejection fraction) is 50% or higher.
- You were hospitalized for heart failure at least once in the last year.
- Your heart failure symptoms are at least NYHA class 2 (you get short of breath during normal activities).
- You have signs of diastolic dysfunction (stiff heart muscle) based on certain tests.
- You have not had a pacemaker, defibrillator, or heart failure pacing device before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
This study compares two procedures for people who have both atrial fibrillation (AFib) and heart failure: one that slows the heart's electrical signals (AV node ablation) and one that helps the heart pump in a more coordinated way (cardiac resynchronization). Both are options when medications alone aren't enough, and the goal is to improve symptoms and quality of life.
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
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