Clin2
NCT06835569Possibly a fitRecruiting

ALTA3263 for advanced KRAS-mutated solid tumors

CancerPDAC - Pancreatic Ductal AdenocarcinomaNSCLC (Non-small Cell Lung Cancer)CRC (Colorectal Cancer)Advanced Solid Tumors

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing clinical trials.

This trial tests an experimental pill called ALTA3263 for adults with advanced solid tumors that have a specific KRAS mutation. It's for people who have already tried other treatments or can't take them.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
448 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your cancer must have a KRAS mutation that was found by a standard genetic test.
  • Your cancer must be advanced (spread or can't be removed) and you've tried other treatments or can't take them.
  • You must be able to take care of yourself (up and about more than 50% of the time).
  • Your organs (kidneys, liver, etc.) must work well enough.
  • You cannot have taken a KRAS-targeting drug before (like sotorasib or adagrasib), and you must be able to swallow pills.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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