Preventing lung injury from breathing machines in ARDS
Part of Lungs & breathing clinical trials.
This study tests a breathing machine strategy to prevent further lung damage in people with severe ARDS. It uses special monitors to guide the machine settings, aiming to protect the lungs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are in the intensive care unit (ICU) with moderate-to-severe ARDS (a serious lung problem).
- Your oxygen level is very low (PaO2/FiO2 less than 200) on a blood test.
- You are able to have special monitoring: a tube to measure pressure in your esophagus and a chest band to see lung images (EIT).
- You or a family member agrees to let your health data be used for this research.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adjusting the breathing machine settings based on lung pressure (driving pressure) can improve how oxygen reaches your blood and help your heart function in people with severe lung injury (ARDS). It aims to find safer ways to support breathing.
This trial tests a special breathing machine strategy that uses pressure measurements from a small tube in your esophagus (food pipe) to protect your heart's right side while treating ARDS caused by pneumonia. It may help if you have severe lung failure and need a ventilator.
This trial tests a new way to adjust the amount of air given by the ventilator to people with a severe lung injury called ARDS. The goal is to see if a specific breathing strategy can help protect the lungs and improve recovery.
This trial studies two ways to measure how much of your lungs can open up again (recruitability) to help doctors set the best breathing machine pressure. It may help improve oxygen levels in patients with severe lung injury.
This study looks at how the level of pressure from a breathing machine affects blood flow back to the heart in people with severe lung injury (ARDS). It may help doctors find the best settings to protect your heart while helping your lungs.
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hear when a new Adult Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.