Adrenaline during heart artery procedure to prevent poor blood flow
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether giving adrenaline (a medicine that helps blood vessels relax) directly into the heart artery during a procedure to open a blocked artery can prevent a complication called 'no reflow' (where blood still doesn't flow well after the blockage is cleared). It is for people having a specific type of heart attack (STEMI) and being treated within 12 hours.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are having a STEMI heart attack (a specific type seen on an ECG) and are being treated within 12 hours of symptoms starting.
- You are not pregnant.
- You do not have certain heart conditions, like a blocked artery that can't be opened (CTO), a tear in the artery wall (SCAD), or a very weak heart (cardiomyopathy).
- You are not in cardiogenic shock (heart too weak to pump blood).
- You do not have uncontrolled high blood pressure (systolic over 180 or diastolic over 110), a serious heart rhythm problem, or an allergy to adrenaline.
- You are willing to give your consent for the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether patients who have had a heart attack with a specific type of artery blockage can be safely treated without placing a metal stent (tube) in their artery. Doctors will monitor whether the blockage stays open on its own.
This study tests different ways of restoring blood flow for people having a heart attack (STEMI) when the usual emergency procedure (primary PCI) may be delayed. It aims to see if giving a clot-busting medicine beforehand is as good as waiting for the procedure, or if another approach works better.
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