Clin2
NCT06852352Possibly a fitRecruiting

Modified brain lymph surgery for Alzheimer's or Parkinson's

Alzheimer DiseaseParkinson Disease

Part of Brain & nervous system, Mental health clinical trials.

This study tests a new, less invasive surgery to improve lymph drainage from the brain. It may help clear harmful proteins linked to Alzheimer's or Parkinson's disease.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
160 people
Ages
50 years to 80 years
Study type
Interventional

Who can take part

  • You are between 50 and 75 years old (for Alzheimer's) or 50 to 80 years old (for Parkinson's).
  • You have mild cognitive impairment or dementia due to Alzheimer's (with a positive amyloid PET scan) OR a diagnosis of Parkinson's disease for more than 2 years.
  • You are generally healthy enough for surgery and imaging tests (MRI, PET, and a dye test called ICG).
  • You do not have serious heart, lung, kidney, or liver problems, active infections, bleeding disorders, or recent cancer.
  • You are not currently using sleeping pills more than twice a week or enrolled in another drug trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06978946Not yet recruiting
Neck lymph bypass surgery for moderate-to-severe dementia

This study tests a surgery that connects tiny lymph vessels in the neck to improve drainage in the brain, which may help people with moderate-to-severe dementia. It aims to see if this surgery can slow down memory loss and improve daily function.

Shanghai, Shanghai Municipality
NCT07294885Recruiting
Lymphatic surgery for Alzheimer's disease

This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.

Shenyang
NCT06965062Recruiting
Neck surgery for Alzheimer's: a first test

This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.

Singapore
NCT07857759Recruiting
Neck lymph node surgery for early Alzheimer's disease

This study tests whether a microsurgery on lymph nodes in the neck can help clear waste from the brain in people with early Alzheimer's. It might slow down memory loss.

Gdansk
NCT07094438Recruiting· Phase 1
Brain stimulation and neck surgery for severe Alzheimer's

This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.

Beijing
NCT06530732Recruiting· Phase 3
Neck drainage surgery for Alzheimer's disease

This study tests a new surgical treatment for Alzheimer's disease. The surgery aims to improve drainage in the neck to help clear waste from the brain. This is a first-of-its-kind pilot study to see if it is safe and might help thinking and memory.

Hangzhou, Zhejiang

Hear when a new Alzheimer Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.