Clin2
NCT06978946Possibly a fitNot yet recruiting

Neck lymph bypass surgery for moderate-to-severe dementia

Alzheimer DiseaseLewy Body Dementia (LBD)Frontotemporal Dementia (FTD)DementiaParkinsons Disease With Dementia (PDD)

Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.

This study tests a surgery that connects tiny lymph vessels in the neck to improve drainage in the brain, which may help people with moderate-to-severe dementia. It aims to see if this surgery can slow down memory loss and improve daily function.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
85 people
Ages
50 years to 80 years
Study type
Interventional

Who can take part

  • You are between 50 and 80 years old.
  • You have been diagnosed with Alzheimer's, frontotemporal, Lewy body, or Parkinson's-related dementia.
  • Your dementia is moderate to severe, based on memory tests and a doctor's assessment.
  • You have been on the same dementia medications for at least one month without changes.
  • You are able to understand the study and give consent.
  • You do not have another cause of dementia (like stroke, head injury, or alcohol use) that would rule you out.
  • You do not have other severe health problems (like major heart, lung, kidney, or liver disease) that would make surgery risky.
  • You have no history of radiation or surgery in the head or neck, and no other reason surgery would be unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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