Neck surgery for moderate-to-severe dementia
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This trial tests a surgical procedure (deep cervical lymphaticovenous anastomosis) for people with moderate-to-severe dementia. The goal is to see if the surgery can improve symptoms by helping the brain's drainage system.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have been diagnosed with Alzheimer's, frontotemporal dementia, dementia with Lewy bodies, or Parkinson's disease dementia.
- Your dementia is moderate to severe (your doctor has confirmed this).
- You have been on the same dementia medications for at least a month.
- You are healthy enough for neck surgery (no major heart, lung, kidney problems, or previous neck surgery/radiation).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new surgery on neck lymph vessels to see if it helps people with Alzheimer's. It is for patients aged 60 to 80 with mild to severe Alzheimer's who have had the diagnosis for over a year.
This study tests a new, less invasive surgery to improve lymph drainage from the brain. It may help clear harmful proteins linked to Alzheimer's or Parkinson's disease.
This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.
This study tests a new surgical treatment for Alzheimer's disease. The surgery aims to improve drainage in the neck to help clear waste from the brain. This is a first-of-its-kind pilot study to see if it is safe and might help thinking and memory.
Hear when a new Frontotemporal Dementia (FTD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.