Study of navlimetostat alone or with izalontamab for advanced lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new drug, navlimetostat, either by itself or combined with another drug, izalontamab, for people with advanced non-small cell lung cancer that has a specific genetic change (MTAP loss). The goal is to see if these treatments can help shrink tumors or slow cancer growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-small cell lung cancer that has spread or cannot be removed by surgery.
- Your tumor has a specific genetic change called MTAP loss (the study will confirm this).
- You have tried at least one prior treatment and your cancer has continued to grow.
- You are 18 years or older.
- You are able to swallow pills whole.
- You have not had treatment with a PRMT5 or MAT2A inhibitor before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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