Clin2
NCT06859255Possibly a fitRecruiting

Comparing heart valves for small aortic openings

Severe Aortic Valve Stenosis

Part of Heart & circulation clinical trials.

This trial compares different types of heart valves (surgical and less-invasive) used in people with a small heart valve opening. It aims to see which valves work best, and will follow up with patients who already had the procedure.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
Any age
Study type
Interventional

Who can take part

  • You had severe narrowing of your aortic valve (aortic stenosis) and got a new valve, either through open-heart surgery (SAVR) or a less invasive procedure (TAVI).
  • The valve you received is one of the specific models and sizes that are being tested in this study.
  • You do not have an untreated bulge in the main artery from your heart (aortic root or ascending aorta aneurysm).
  • You did not have a heart attack or a blocked-artery procedure in the last 12 weeks.
  • You do not have a permanent pacemaker and your heart rhythm is not from a pacemaker (it should be in normal sinus rhythm).
  • You do not have a moderate or severe leak around the valve (paravalvular leak).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta

This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.

Beijing, Beijing Municipality
NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve

This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.

Beijing
NCT06009588Recruiting
Comparing Two Heart Valve Types for Aortic Stenosis with Aorta Dilation

This trial tests two types of artificial heart valves—one that expands on its own and one expanded with a balloon—in people with a widened upper aorta. The goal is to see which works better for your condition.

Beijing, Beijing Municipality
NCT07532317Not yet recruiting
Testing a new heart valve for moderate aortic stenosis

This study compares a new artificial aortic valve (Myval THV) with standard medical treatment for people with moderate aortic stenosis—a condition where the heart valve doesn't open fully. The trial tests whether the new valve can help improve symptoms and heart function.

NCT05991271Not yet recruiting
Studying a new valve for tight heart valve

This trial tests a new heart valve device (Venus-Vitae) for people with severe aortic stenosis, a condition where the heart valve is too tight. It aims to see if the device works well for patients of all surgical risk levels.

NCT07125469Recruiting
Comparing CT scan measurements to surgery findings for aortic valve replacement

This study checks if measurements taken from a CT scan before surgery match the actual size of the valve measured during surgery. It may help doctors choose the best valve size for people with severe aortic stenosis who need valve replacement.

Cotignola, Ravenna

Hear when a new Severe Aortic Valve Stenosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.