Clinical trials
Joint Pain clinical trials
Below are recruiting joint pain clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT07238478Recruiting
Supplement for menopause quality of life in postmenopausal women
This trial tests a dietary supplement to see if it can improve menopause-related symptoms, like hot flashes and joint discomfort, in healthy postmenopausal women.
Harrison, New YorkAges 50–70 - NCT05909709RecruitingPhase 1
Tested injections for chronic facet-related back pain
This Phase 1 study tests the safety of an injection called Alocyte in adults with long-lasting back pain coming from the facet joints. If you qualify, you may be followed closely to check side effects and how you respond over multiple visits.
North Miami, FloridaAges 18 years+ - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT06081101RecruitingEarly Phase 1
Comparing two injections for sacroiliac joint pain
This trial compares two types of pain-relieving injections for sacroiliac joint pain. One is a common anti-inflammatory (ketorolac), and the other is a steroid. The goal is to see which works better and lasts longer.
Hamilton, OntarioAges 18 years+ - NCT07119645Recruiting
Collagen supplement for knee discomfort relief
This trial tests whether a daily collagen supplement (NT-II™) can reduce knee discomfort during activities like walking or climbing stairs. You may qualify if you have mild to moderate knee pain during exercise, no arthritis, and are generally healthy.
San Francisco, CaliforniaAges 20–65 - NCT07179016Recruiting
Acupressure for chronic pain in rural areas
This trial tests if a self-managed acupressure program can help people living in rural areas manage long-term muscle or joint pain, like neck, back, or knee pain. You would learn to press small seeds on your ear to ease pain.
Columbia, South CarolinaAges 18–85 - NCT05961800Recruiting
Study ways to evaluate lumbar back pain blocks
This study looks at how well different methods can evaluate a common procedure used for chronic low back pain (lumbar medial branch blocks). If you have long-lasting, everyday back pain and are having this procedure, you may help researchers compare evaluation approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT07814729Recruiting
Sacral block for chronic sacroiliac joint pain
This study tests whether adding a nerve block near the sacrum to a standard sacroiliac joint injection gives more pain relief. It's for people with long-term sacroiliac joint pain that hasn't improved with other treatments.
Al FayyumAges 21–60 - NCT07490938Recruiting
Acupuncture for joint pain from breast cancer hormone therapy
This trial compares two types of acupuncture (electroacupuncture and ear acupressure) with standard care to see if they can help relieve joint pain caused by hormone therapy for breast cancer. It may be a good option if you have ongoing joint pain and are continuing hormone therapy.
Wuhan, HubeiAges 18–75 - NCT07304557Recruiting
Exercise therapy for jaw joint disorders
This study tests whether specific exercises can reduce pain and improve jaw and tongue function in people with temporomandibular joint disorder (TMD). It may help if you have jaw pain or clicking and have not had recent neck or jaw therapy.
Ankara, ALTINDAGAges 18–65 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07839195Enrolling by invitationPhase 2
Steroid injection after radiofrequency ablation for back and neck pain
This trial tests whether giving a corticosteroid injection right after a radiofrequency nerve ablation (a procedure that zaps nerve endings to reduce pain) can help prevent the temporary nerve irritation that sometimes happens after. It may help make your recovery more comfortable.
BangkokAges 18 years+ - NCT07867405Recruiting
Sheep tail fat for knee arthritis pain
This study tests whether applying sheep tail fat to the knee can reduce pain, stiffness, and make daily activities easier for people with knee arthritis (gonarthrosis). It may be an option if you have had knee pain for at least three months and want a natural, non-drug treatment to try at home.
BitlisAges 18 years+ - NCT07547215Recruiting
TRAQ Minimally Invasive Sacroiliac Joint Fusion Study
This study tests a minimally invasive surgical procedure called TRAQ to treat chronic sacroiliac joint (SIJ) pain—a type of lower back and buttock pain. The procedure may help if you've had pain for at least 6 months that didn't improve with non-surgical treatments and have already benefited from diagnostic joint injections.
Tucson, ArizonaAges 21 years+ - NCT05424198Recruiting
A new device for neck pain treatment compared to the standard one
This study tests a new device that uses heat to treat neck pain that has lasted at least 3 months. It compares the new device to the standard one to see if it works better or is safer.
Farmington, UtahAges 18 years+ - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT07333417Recruiting
Rigid taping for acromioclavicular joint degeneration
This study tests whether a special rigid tape applied to the shoulder can reduce pain and improve function in people with acromioclavicular (AC) joint degeneration. The AC joint is where your collarbone meets the top of your shoulder blade, and this condition can cause pain and stiffness.
Ankara, AnkaraAges 18–65 - NCT02329093Recruiting
Hip osteoarthritis with pain, testing non-weight bearing
This study looks at whether reducing weight on the hip can help slow how hip arthritis shows up on X-rays in people who have hip joint pain. It may be an option if your pain is from hip arthritis rather than a clear fracture.
Matsumoto, NaganoAges Any age - NCT07766720Recruiting
Eggshell membrane and turmeric supplements for exercise recovery
This trial tests whether taking eggshell membrane, curcumin (turmeric), or both together can help your muscles recover faster after intense exercise. It may reduce soreness and help you bounce back sooner.
College Station, TexasAges 18–40 - NCT05447338Recruiting
Manual therapy for neck pain with limited neck motion
This trial tests whether hands-on/manual physical therapy helps people with neck pain and reduced neck movement. It may help improve motion and reduce symptoms if your neck pain fits the trial’s type and severity.
CórdobaAges 25–50 - NCT07058220Recruiting
Neck training for neck pain relief
This trial tests whether special neck position-sense exercises can help people with general neck pain feel better. It may be a good option if you have neck pain without a specific injury.
GizaAges 25–45
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Common questions
- Are there clinical trials for joint pain?
- Yes. Clin2 currently lists 87 recruiting joint pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a joint pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a joint pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.