Light therapy for early mouth lesions
Part of Cancer, Mouth & dental, Skin clinical trials.
This trial tests a low-cost light therapy to treat precancerous mouth lesions (moderate to severe dysplasia or carcinoma in situ) that are at least 10 mm. The treatment uses a special light to destroy abnormal cells, possibly avoiding surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a mouth lesion (at least 10 mm) that was biopsied and shows moderate or severe dysplasia, or carcinoma in situ (not invasive cancer).
- You are 18 or older and can give consent.
- You are willing to come for follow-up visits for at least one year.
- You are generally well enough (able to do daily activities; no serious uncontrolled health issues).
- Your blood tests (liver, kidney, blood counts) are within acceptable ranges.
- You are not pregnant or breastfeeding, and you avoid certain supplements and photosensitizing medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two topical treatments for oral leukoplakia, a white patch in the mouth that can become cancer. One treatment uses light-activated therapy (photodynamic therapy), and the other uses a vitamin D cream (calcipotriol).
This trial tests two light-based treatments (photobiomodulation and photodynamic therapy) and a steroid cream (clobetasol) for painful oral lichen planus. The goal is to see which treatment works best to reduce mouth sores and discomfort.
This study tests a special light technique (narrow band imaging) to find early signs of mouth cancer or pre-cancer during a regular check. It may help doctors spot problems sooner and guide biopsy decisions.
This trial uses a special light-based scanner (OCT) and artificial intelligence to help diagnose early signs of mouth cancer or precancer. It aims to see if this combination can make diagnosis easier and more accurate.
This study is testing a new, quick, and painless way to check suspicious mouth spots for early signs of cancer using a special light and artificial intelligence. It aims to help doctors decide faster whether a biopsy is needed, potentially making diagnosis easier and more accurate.
This trial tests two ways of giving light therapy (photobiomodulation) to prevent or treat painful mouth sores caused by radiation therapy for head and neck cancers. It aims to see which method works better and is more comfortable for patients.
Hear when a new Oral Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.