Clot-busting treatment after stroke while on Factor Xa inhibitor
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You took a Factor Xa inhibitor (like apixaban, rivaroxaban, edoxaban, or betrixaban) within the last 48 hours, or you are currently prescribed one.
- You are having a disabling stroke and can get treatment within 4.5 hours of symptom start (or have a special MRI if you woke up with symptoms).
- You do not have a large brain artery clot that can be removed by a procedure within 30 minutes.
- You do not have a bleeding disorder, recent major surgery, or serious bleeding risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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