Clin2
NCT06908772Likely a fitNot yet recruiting

Combination drug study for advanced lung cancer

Recurrent or Metastatic NSCLC Patients With Classical EGFR Mutations Accompanied by MET Amplification or Overexpression

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new combination of two targeted drugs, glumetinib and osimertinib, for people with advanced non-small cell lung cancer (NSCLC). The goal is to see if the combination can help control the cancer better than standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
390 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have been diagnosed with non-small cell lung cancer (NSCLC) that has spread and cannot be removed by surgery.
  • You must have at least one tumor that can be measured on scans.
  • You must be able to take care of yourself (able to do daily activities without needing help).
  • You must not have received treatment with an EGFR inhibitor or MET inhibitor before.
  • You must not have cancer that has spread to the lining of the brain or cause symptoms with brain metastases.
  • You must be willing to avoid certain medications that could interact with the study drugs.
  • If you are of childbearing potential, you must use highly effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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