Reversing radiation side effects in head and neck cancer
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had head and neck cancer, and it's now under control (no active disease).
- You received radiation therapy to your neck, with a dose of at least 30 Gray (a unit of radiation).
- You have swelling or hardening of tissues (lymphedema or fibrosis) in your neck or mouth that started more than 6 months after radiation.
- You do not have active liver disease, diabetes, or a history of heart attack or severe heart disease.
- You are not allergic to statins (like Lipitor) or caffeine-like substances.
- You are not pregnant, and if you are a woman of childbearing age, you are not post-menopausal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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