Surgery for Aortic Valve in Low Risk Patients
Part of Heart & circulation clinical trials.
This trial tests if surgery to replace your aortic valve is safe and effective for people with severe aortic stenosis who are at low risk for complications. It compares surgery to another procedure to see which works best.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic valve confirmed by an echocardiogram (ultrasound of the heart) in the past 3 months.
- You have symptoms like trouble breathing, chest pain, or fainting, or your heart's pumping function is below 50%.
- Your heart team says your risk of dying from surgery is under 4% based on your overall health.
- You have not had heart surgery or a chest tube before.
- Your other heart valves are not severely damaged, and you do not have blockages in your leg arteries that would prevent a catheter procedure.
- You are willing and able to give written informed consent to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a less invasive valve replacement (TAVI) can be done safely in hospitals that don't have a full heart surgery team on site. If you have severe aortic stenosis and are 70 or older, this trial might offer a new option with a shorter recovery than open-heart surgery.
This study tests a catheter-based procedure to replace a narrowed aortic valve without traditional open-heart surgery. It's designed for patients who are at higher risk for surgery due to age, health conditions, or anatomy.
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
This study looks at whether replacing a narrowed heart valve early helps people who have severe aortic stenosis but no symptoms. You would be randomly assigned to early valve replacement or careful waiting with regular check-ups.
This trial looks at placing a new aortic valve through the groin (transfemoral) without needing on-site heart surgery for people who are considered very high risk for standard open-heart valve surgery. It aims to measure early outcomes to see how safe and effective this approach is for frail or complex patients.
This study looks at how safe and effective emergency aortic valve replacement is for people with severe aortic stenosis, a condition where the heart's main valve becomes narrow. It aims to help patients who are in critical condition, such as those in shock or with dangerous heart rhythms, by replacing the valve urgently.
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