Precision dosing of antibiotics for critically ill children
Part of Infections clinical trials.
This trial tests a personalized dosing approach for certain antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam, and meropenem) in hospitalized children with serious infections. The goal is to adjust the dose based on blood tests to make sure each child gets the right amount of medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Children from newborn up to 17 years 10 months old
- Admitted to the NICU, PICU, or pediatric hematology-oncology unit
- Has a confirmed or strongly suspected serious infection
- Will start one of these IV antibiotics: amoxicillin-clavulanic acid, piperacillin-tazobactam, or meropenem, expected to be given for at least 2 days
- Not currently on dialysis, ECMO, body cooling, or expected to pass away soon
- No allergy to the assigned antibiotic and not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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