Antibiotic penetration in critically ill children
This study looks at why some antibiotics given through a vein may reach infections differently in very sick children. It aims to make sure medicines are given in the best way to help children in the intensive care unit recover.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be treated in a children’s intensive care unit
- Be between 1 month and 15 years old
- Be getting one of these IV antibiotics: piperacillin-tazobactam, meropenem, or amoxicillin-clavulanic acid
- Need medicine to keep you calm and pain-free (continuous sedation) while a small catheter is placed
- Have an artery line or another IV line for blood tests
- Not have a bleeding disorder, a very low platelet count, or take blood-thinning medicine
- Not be allergic to beta-lactam antibiotics like penicillin
- Not be pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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