Best ECMO flow for cardiogenic shock in the first 48 hours
Part of Heart & circulation clinical trials.
This trial is testing the best blood flow from a heart-lung machine (VA ECMO) to protect your organs and help your heart recover during the first critical days of cardiogenic shock.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with cardiogenic shock, meaning your heart is too weak to pump enough blood.
- You have been on a heart-lung machine called VA ECMO for less than 48 hours.
- Your ECMO was not started because of a cardiac arrest that didn't respond to treatment.
- You did not have a cardiac arrest with low blood flow lasting more than 30 minutes before the shock.
- You are not receiving very high doses of blood pressure medicines (like norepinephrine, vasopressin, dobutamine, or epinephrine).
- You are not pregnant, breastfeeding, or in another study that would prevent participation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
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This trial looks at a “precision” strategy for people in severe heart-related shock who are starting VA ECMO (a life-support machine). It will be done through a hospital registry system, which helps doctors learn which patients benefit most and why.
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