Finding the best dose of numbing medicine for knee surgery pain
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests different amounts of a long-lasting numbing medicine (liposomal bupivacaine) injected near the nerve in your thigh to see which volume works best for controlling pain after knee surgery. If you qualify, you may receive better pain relief and need fewer opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for knee surgery with general anesthesia.
- You are between 18 and 65 years old.
- Your body mass index (BMI) is 35 or less.
- You do not have nerve damage in your thigh, a bleeding disorder, an allergy to numbing medicines, or an infection near the injection site.
- You do not have long-term pain or regularly take strong painkillers (opioids).
- You are not pregnant, and you do not have diabetes with nerve damage.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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