Low sodium oxybate for nighttime cluster headache attacks
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a low-salt version of a medication called sodium oxybate to see if it can reduce cluster headache attacks that happen at night. It may be an option for people whose attacks are not controlled by other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have chronic cluster headache (attacks for at least a year with short breaks or no breaks).
- You have at least 4 night-time attacks per week (between 10 pm and 8 am) on different nights.
- You are not taking other cluster headache prevention meds, or have been on a stable dose for at least 4 weeks.
- You have not had a nerve block injection or oral steroids (prednisone) in the last 3 months.
- You do not have sleep apnea, severe depression, or take certain other medications (like opioids, valproic acid, or sedatives).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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