Low sodium oxybate for hypersomnia with POTS
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether low sodium oxybate, a medication that improves alertness, can help reduce symptoms like dizziness and fatigue in people who have both idiopathic hypersomnia and POTS. You would stay on your current daytime medications, but some heart-related drugs may be paused temporarily before tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older
- You must have a diagnosis of idiopathic hypersomnia (excessive sleepiness not caused by another condition)
- You must have a diagnosis of postural tachycardia syndrome (POTS, a condition causing dizziness and rapid heart rate when standing)
- You must never have taken oxybate (a medication for sleep disorders)
- You must score at least 40 on the COMPASS 31 questionnaire (a measure of autonomic symptoms)
- You must be willing to use reliable birth control if you are of childbearing age
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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