LSD for cluster headaches in a clinical study
Part of Brain & nervous system clinical trials.
This Phase 2 study tests whether a supervised dose of LSD (or a placebo) can reduce cluster headache attacks. It’s for people whose cluster headaches respond to oxygen, and who can safely pause certain medications and substances around the dosing day.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 25 to 75
- Have chronic cluster headache, or episodic cluster headache that keeps returning and is expected to continue
- Your headache attacks must respond to oxygen
- Be able to understand the study and sign consent, and agree to follow all rules
- Agree to pause preventive and “rescue/abort” headache medicines (except oxygen) around the dosing time, plus stop certain psychiatric and other substances as instructed
- You must not drive or use machines for 24 hours after the LSD/placebo dose
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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