Tenecteplase for stroke treatment 24-72 hours after symptoms start
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if the clot-busting drug tenecteplase can help people with a moderate to severe stroke when given 24 to 72 hours after symptoms began. It aims to see if this later treatment window can improve recovery and reduce disability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- Your stroke symptoms started between 24 and 72 hours ago (or you were last seen well that long ago)
- You had little or no disability before the stroke (able to do daily activities independently)
- Your stroke is moderate to severe (NIHSS score 6-25, or 4-5 with a disabling symptom like vision loss or trouble speaking)
- Brain scans show a blocked artery and a mismatch between the area at risk and the already damaged area
- You are not at high risk of bleeding and have no recent major surgery, stroke, or bleeding issues
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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