Study of mezagitamab for IgA nephropathy
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a new drug called mezagitamab for adults with IgA nephropathy, a kidney condition. The study aims to see if this drug can help reduce protein in the urine and preserve kidney function. You may be eligible if your kidney function is above a certain level and your urine protein is high enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of IgA nephropathy confirmed by a kidney biopsy within the last 10 years.
- Your kidney function (eGFR) must be above 30 mL/min/1.73m² at screening.
- You need to have a certain level of protein in your urine (at least 0.8 grams per gram of creatinine or 1 gram per day).
- Your blood pressure must be controlled (systolic 150 or lower, diastolic 100 or lower) and you should be on stable blood pressure medication.
- You cannot have received a treatment targeting CD38 (the protein this drug works on) before joining the trial.
- You must be 18 years or older and willing to follow the trial's rules, including using effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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