Ulinastatin and thymosin for immune support after aortic dissection surgery
Part of Heart & circulation clinical trials.
This trial tests whether two anti-inflammatory drugs, ulinastatin and thymosin α1, can help protect your immune system and organs after emergency surgery for a torn aorta (aortic dissection). If you qualify and take part, you may receive these medications in addition to standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were diagnosed with an aortic dissection (a tear in the main artery) within the last 2 weeks.
- You need emergency surgery to fix the torn aorta.
- You are between 18 and 90 years old.
- You do not have a known allergy to either study drug (ulinastatin or thymosin α1).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
This trial is studying treatments for people with a sudden tear in the main artery from the heart (type A aortic dissection) or a similar condition. It aims to improve outcomes after this emergency.
This trial tests whether ketorolac, a common pain reliever, can improve outcomes and prognosis for people having emergency surgery for a type A aortic dissection. If you are eligible and choose to join, you may receive ketorolac in addition to standard care.
This study compares two surgical techniques for repairing a tear in the main artery (aorta) during an emergency. It aims to see if adding a stent (a small mesh tube) to the standard repair improves outcomes. Participation may help improve treatment for this serious condition.
This trial tests whether using artificial intelligence to guide treatment choices can improve recovery in people with a sudden tear in the main artery (aortic dissection). All participants will receive emergency surgery, but the AI may help doctors tailor the approach to each person's condition, potentially reducing complications.
This study tests whether an “add-on” anti-inflammatory approach can help after surgery for certain problems affecting the aorta (the body’s main artery) soon after symptoms begin. It may be designed to reduce inflammation-related complications in people who are treated quickly and can join follow-up.
Hear when a new Aortic Dissection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.