Sivelestat for lung protection during emergency aortic surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Type A acute aortic syndrome (a serious tear in the main artery from the heart) within the last 2 weeks.
- You are scheduled to have emergency heart or aorta surgery.
- You are between 18 and 90 years old.
- You agree to join the study and sign a consent form.
- You are not allergic to the study drug sivelestat sodium.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial uses artificial intelligence to help choose the best emergency surgery for people with a sudden tear in the main artery of the body (acute aortic dissection). It aims to improve outcomes by matching the treatment to each patient's specific condition.
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This trial tests if the drug Sivelestat can protect organs like the heart, kidneys, and lungs after emergency surgery for a severe tear in the main artery from the heart (type A aortic dissection). If you are having this surgery, you may be able to join.
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