MRG003 plus pucotenlimab vs chemo for advanced nasopharyngeal cancer
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This trial tests whether combining an experimental antibody-drug conjugate (MRG003) with an immunotherapy (pucotenlimab) works better than standard chemotherapy for people with nasopharyngeal cancer that has come back or spread. If you have tried at least one prior treatment and are generally in good health, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have nasopharyngeal cancer that has returned or spread and failed at least one prior treatment
- You are expected to live at least 3 months
- You have at least one measurable tumor (visible on scans)
- You are able to do daily activities with little or no help (ECOG 0 or 1)
- Your heart and organ functions are adequate, including a normal heart-pumping ability
- If you could become pregnant or get someone pregnant, you must use effective birth control during treatment and for 6 months after
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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