Testing two new drugs for FGF19-positive liver cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests two new targeted drugs (ABSK-011 and ABSK043) for people with advanced liver cancer whose tumors have high levels of the FGF19 protein and who have already tried at least one other treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with a type of liver cancer called hepatocellular carcinoma (HCC).
- Your cancer has grown or spread after at least one previous treatment.
- A lab test shows your tumor has high levels of a protein called FGF19.
- You are able to take care of yourself (ECOG score 0 or 1).
- You have not taken a drug that blocks FGFR (a protein) before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new drug, ABSK-011, combined with standard care, against a placebo with standard care for people with advanced liver cancer that has a specific marker called FGF19 overexpression. The goal is to see if ABSK-011 can help slow the disease.
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